Recombinant Human Cytokeratin 4 protein (ab112314)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P19013
    • 生物種Human
    • 配列MIARQQCVRGGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSR SLYNLRGNKSISMSVAGSRQGACFGGAGGFGTGGFGAGGFGAGFGTGGFG GGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDPEIQKVRTE EREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEP LFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTA AENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTH VSDTSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQ LQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADA EQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVKLALDIEI ATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLSS GFGSGSGSGFGFGGSVSGSSSSKIISTTTLNKRR
    • 分子量85 kDa including tags
    • 領域1 to 534
    • タグGST tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab112314 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    ELISA

    Western blot

  • 製品の状態Liquid
  • 備考ab112314 is best use within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione

関連情報

  • 別名
    • CK 4
    • CK-4
    • CK4
    • CYK4
    • Cytokeratin 4
    • Cytokeratin-4
    • Cytokeratin4
    • FLJ31692
    • K2C4_HUMAN
    • K4
    • Keratin
    • Keratin 4
    • Keratin type II cytoskeletal 4
    • Keratin-4
    • Keratin4
    • KRT 4
    • Krt4
    • type II cytoskeletal 4
    • Type-II keratin Kb4
    see all
  • 組織特異性Detected in the suprabasal layer of the stratified epithelium of the esophagus, exocervix, vagina, mouth and lingual mucosa, and in cells and cell clusters in the mucosa and serous gland ducts of the esophageal submucosa (at protein level). Expressed widely in the exocervix and esophageal epithelium, with lowest levels detected in the basal cell layer.
  • 関連疾患Defects in KRT4 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.
  • 配列類似性Belongs to the intermediate filament family.
  • Information by UniProt

Recombinant Human Cytokeratin 4 protein 画像

  • 12.5% SDS-PAGE showing ab112314 stained with Coomassie Blue.

Recombinant Human Cytokeratin 4 protein (ab112314) 使用論文

ab112314 has not yet been referenced specifically in any publications.

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