Recombinant Human Cytokeratin 3 protein (ab114414)

製品の概要

  • 製品名
    Recombinant Human Cytokeratin 3 protein
  • タンパク質長
    Protein fragment

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      LLQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMED LVEDFKKK
    • 分子量
      32 kDa including tags
    • 領域
      232 to 289

特性

Our Abpromise guarantee covers the use of ab114414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    ELISA

    SDS-PAGE

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • 65 kDa cytokeratin
    • CK-3
    • CK3
    • Cytokeratin-3
    • K2C3_HUMAN
    • K3
    • Keratin
    • Keratin 3
    • Keratin type II cytoskeletal 3
    • Keratin-3
    • KRT3
    • type II cytoskeletal 3
    • Type-II keratin Kb3
    see all
  • 組織特異性
    Cornea specific.
  • 関連疾患
    Defects in KRT3 are a cause of Meesmann corneal dystrophy (MECD) [MIM:122100]; also abbreviated as MCD and known as juvenile epithelial corneal dystrophy of Meesmann. MECD is an autosomal dominant disease that causes fragility of the anterior corneal epithelium. Patients are usually asymptomatic until adulthood when rupture of the corneal microcysts may cause erosions, producing clinical symptoms such as photophobia, contact lens intolerance and intermittent diminution of visual acuity. Rarely, subepithelial scarring causes irregular corneal astigmatism and permanent visual impairment. Histological examination shows a disorganized and thickened epithelium with widespread cytoplasmic vacuolation and numerous small, round, debris-laden intraepithelial cysts.
  • 配列類似性
    Belongs to the intermediate filament family.
  • Information by UniProt

画像

  • 12.5% SDS-PAGE stained with Coomassie Blue.

参考文献

ab114414 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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