Recombinant Human Cytokeratin 16 protein (ab114405)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P08779
    • 生物種Human
    • 配列RRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQ LSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQ
    • 分子量36 kDa including tags
    • 領域301 to 398

特性

Our Abpromise guarantee covers the use of ab114405 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    Western blot

    SDS-PAGE

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • CK 16
    • CK-16
    • CK16
    • Cytokeratin-16
    • Cytokeratin16
    • FNEPPK
    • Focal non epidermolytic palmoplantar keratoderma
    • K 16
    • K16
    • K1C16_HUMAN
    • K1CP
    • Keratin
    • Keratin 1 type I
    • Keratin 16
    • Keratin type I cytoskeletal 16
    • Keratin-16
    • Keratin16
    • KRT 16
    • Krt16
    • KRT16A
    • NEPPK
    • PC1
    • type I cytoskeletal 16
    see all
  • 組織特異性Expressed in the hair follicle, nail bed and in mucosal stratified squamous epithelia and, suprabasally, in oral epithelium and palmoplantar epidermis. Also found in luminal cells of sweat and mammary gland ducts.
  • 関連疾患Defects in KRT16 are a cause of pachyonychia congenita type 1 (PC1) [MIM:167200]; also known as Jadassohn-Lewandowsky syndrome. PC1 is an autosomal dominant ectodermal dysplasia characterized by hypertrophic nail dystrophy resulting in onchyogryposis (thickening and increase in curvature of the nail), palmoplantar keratoderma, follicular hyperkeratosis, and oral leukokeratosis. Hyperhidrosis of the hands and feet is usually present.
    Defects in KRT16 are the cause of palmoplantar keratoderma non-epidermolytic focal (FNEPPK) [MIM:613000]. A dermatological disorder characterized by non-epidermolytic palmoplantar keratoderma limited to the pressure points on the balls of the feet, with later mild involvement on the palms. Oral, genital and follicular keratotic lesions are often present.
    Defects in KRT16 are a cause of unilateral palmoplantar verrucous nevus (UPVN) [MIM:144200]. UPVN is characterized by a localized thickening of the skin in parts of the right palm and the right sole.
    Note=KRT16 and KRT17 are coexpressed only in pathological situations such as metaplasias and carcinomas of the uterine cervix and in psoriasis vulgaris.
  • 配列類似性Belongs to the intermediate filament family.
  • Information by UniProt

Recombinant Human Cytokeratin 16 protein 画像

  • 12.5% SDS-PAGE analysis of ab114405, stained with Coomassie Blue.

Recombinant Human Cytokeratin 16 protein (ab114405) 使用論文

ab114405 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab114405.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"