Recombinant Human Cytochrome P450 1A2 protein (ab114370)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P05177
    • 生物種Human
    • 配列ESSDEMLSLVKNTHEFVETASSGNPLDFFPILRYLPNPALQRFKAFNQRF LWFLQKTVQEHYQDFDKNSVRDITGALFKHSKKGPRASGNLIPQEKIVNL
    • 分子量37 kDa including tags
    • 領域211 to 310

特性

Our Abpromise guarantee covers the use of ab114370 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • Aryl hydrocarbon hydroxylase
    • CP 12
    • CP12
    • CP1A2_HUMAN
    • CYP1A2
    • CYPIA2
    • Cytochrome P(3)450
    • Cytochrome P450 1A2
    • Cytochrome P450 4
    • Cytochrome P450 family 1 polypeptide 2
    • Cytochrome P450 family 1 subfamily A polypeptide 2
    • Cytochrome P450 subfamily I aromatic compound inducible polypeptide 2
    • Cytochrome P450-P3
    • Cytochrome P4501A2
    • Dioxin inducable P3 450
    • Flavoprotein linked monooxygenase
    • Microsomal monooxygenase
    • P(3)450
    • P3 450
    • P450 4
    • P450 form 4
    • P450 P3
    • P450(PA)
    • Xenobiotic monooxygenase
    see all
  • 機能Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.
  • 組織特異性Liver.
  • 配列類似性Belongs to the cytochrome P450 family.
  • 細胞内局在Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt

Recombinant Human Cytochrome P450 1A2 protein 画像

  • 12.5% SDS-PAGE wtih ab114370 at 36.63kDa stained with Coomassie Blue.

Recombinant Human Cytochrome P450 1A2 protein (ab114370) 使用論文

ab114370 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab114370.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"