Recombinant Human Cyclin E1 protein (ab119719)

製品の概要

法規制情報

製品の詳細

  • 由来
    Recombinant
  • 由来
    Baculovirus infected Sf9 cells
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 分子量
      73 kDa including tags
    • 領域
      1 to 410

特性

Our Abpromise guarantee covers the use of ab119719 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    SDS-PAGE

  • 精製度
    > 90 % SDS-PAGE.
    Purity tested by densitometry.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 25% Glycerol, 0.79% Tris HCl, 0.88% Sodium chloride, 0.31% Glutathione, 0.003% EDTA, 0.003% DTT, 0.002% PMSF

関連情報

  • 別名
    • CCNE
    • Ccne1
    • CCNE1_HUMAN
    • cyclin E variant ex5del
    • cyclin E variant ex7del
    • Cyclin E1
    • Cyclin Es
    • Cyclin Et
    • CyclinE
    • G1/S specific cyclin E
    • G1/S-specific cyclin-E1
    see all
  • 機能
    Essential for the control of the cell cycle at the G1/S (start) transition.
  • 組織特異性
    Highly expressed in testis and placenta. Low levels in bronchial epithelial cells.
  • 配列類似性
    Belongs to the cyclin family. Cyclin E subfamily.
  • 翻訳後修飾
    Phosphorylation of Thr-395 by GSK3 and of Ser-399 by CDK2 accelerates degradation via the ubiquitin proteasome pathway. Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在
    Nucleus.
  • Information by UniProt

画像

  • SDS Page analysis of ab119719

参考文献

ab119719 has not yet been referenced specifically in any publications.

レビューと Q&A

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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