Recombinant human CTGF protein (ab50044)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P29279
    • 生物種Human
    • 配列GKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLP VEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA
    • 分子量11 kDa
    • 領域253 to 349

関連製品

特性

Our Abpromise guarantee covers the use of ab50044 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性

    Biological Activity : Determined by the dose-dependent stimulation of the proliferation of HUVEC cells. The expected ED50 for this effect is 1.0-2.0 µg/ml.

  • アプリケーション

    SDS-PAGE

    Functional Studies

  • 精製度> 95 % SDS-PAGE.
    Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

    Spin down vial and reconstitute in distilled water for a concentration of 0.1 - 1.0 mg/ml.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • CCN 2
    • CCN family member 2
    • CCN2
    • Connective tissue growth factor
    • Ctgf
    • CTGF_HUMAN
    • Hcs 24
    • Hcs24
    • Hypertrophic chondrocyte specific protein 24
    • Hypertrophic chondrocyte-specific gene product 24
    • Hypertrophic chondrocyte-specific protein 24
    • IBP-8
    • IGF-binding protein 8
    • IGFBP-8
    • IGFBP8
    • Insulin like Growth Factor Binding Protein 8
    • Insulin-like growth factor-binding protein 8
    • MGC102839
    • NOV 2
    • NOV2
    see all
  • 機能Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
  • 組織特異性Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.
  • 配列類似性Belongs to the CCN family.
    Contains 1 CTCK (C-terminal cystine knot-like) domain.
    Contains 1 IGFBP N-terminal domain.
    Contains 1 TSP type-1 domain.
    Contains 1 VWFC domain.
  • 細胞内局在Secreted > extracellular space > extracellular matrix. Secreted.
  • Information by UniProt

Recombinant human CTGF protein (ab50044) 使用論文

ab50044 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us.

I can confirm that ab50044 can be used as a control in sELISA involving ab84244 and ab109606.

Please be advised the conditions and dilutions has to be determined by end use.

I hope this infor...

Read More

My previous statement was incorrect. These, ab50044 and ab61847, appear to be the same fragment, but it is not clear to me if both products have both been assayed for activity. Only the ab50044 datasheet includes a note about stimulation of HUVEC proli...

Read More

The protein ab69786 has not, to our knowledge, been tested for activity. The other two are the same fragment, different from the ab69786 fragment, and both appear to have been tested for activity, though only the ab50044 datasheet mentions the testing ...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"