Recombinant Human CTDSP1 protein (ab124856)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q9GZU7
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMDSSAVITQISKEEARGPLRGKGDQKSAAS QKPRSRGILHSLFCCVCRDDGEALPAHSGAPLLVEENGAIPKTPVQYLLP EAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLK RPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESC VFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSD TELHDLLPFFEQLSRVDDVYSVLRQPRPGS
    • 分子量31 kDa including tags
    • 領域1 to 260
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab124856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 90 % SDS-PAGE.
    ab124856 is purified by proprietary chromatographic techniques and sterile filtered.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

関連情報

  • 別名
    • Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 1
    • Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
    • CTD (carboxy terminal domain RNA polymerase II polypeptide A) small phosphatase 1
    • CTDS1_HUMAN
    • CTDSP1
    • NIF3
    • NLI IF
    • NLI interacting factor 3
    • NLI-IF
    • NLI-interacting factor 3
    • NLIIF
    • Nuclear LIM interactor interacting factor 3
    • Nuclear LIM interactor-interacting factor 3
    • SCP1
    • Small C-terminal domain phosphatase 1
    • Small CTD phosphatase 1
    see all
  • 機能Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
  • 組織特異性Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta.
  • 配列類似性Contains 1 FCP1 homology domain.
  • 細胞内局在Nucleus. Colocalizes with RNA polymerase II.
  • Information by UniProt

Recombinant Human CTDSP1 protein (ab124856) 使用論文

ab124856 has not yet been referenced specifically in any publications.

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