Recombinant human COX2 / Cyclooxygenase 2 protein (ab58868)

製品の概要

法規制情報

製品の詳細

  • 由来Recombinant
  • 由来Baculovirus infected Sf21 cells
  • アミノ酸配列
    • アクセッション番号P35354
    • 生物種Human
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab58868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性Specific Activity: minimum 8,000 units per mg protein
  • アプリケーション

    Functional Studies

    SDS-PAGE

    Western blot

    Other

  • 製品の状態Liquid
  • 備考This protein is relatively unstable at room temperature; Keep the enzyme on ice (0 °C to 4 °C) at all times.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: 300µM diethyldithio-carbamate (DDC)
    Constituents: 0.1% Tween 20, 80mM Tris HCl, pH 8

    Note: If this preservative (DDC) is undesirable, it can be removed by standard desalting procedures, but the enzyme is unstable in the absence of the preservative and so should be used within one hour.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • COX 2
    • COX-2
    • COX2
    • Cyclooxygenase
    • Cyclooxygenase 2
    • Cyclooxygenase 2b
    • Cyclooxygenase-2
    • Cyclooxygenase2
    • EC 1.14.99.1
    • fj02a10
    • Glucocorticoid-regulated inflammatory cyclooxygenase
    • Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase
    • GRIPGHS
    • hCox 2
    • Macrophage activation-associated marker protein P71/73
    • OTTHUMP00000033524
    • PES-2
    • PGG/HS
    • PGH synthase 2
    • PGH2_HUMAN
    • PGHS 2
    • PGHS-2
    • PGHS2
    • PHS 2
    • PHS II
    • PHS2
    • Prostaglandin endoperoxide synthase 2
    • Prostaglandin endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
    • Prostaglandin G/H synthase
    • Prostaglandin G/H synthase 2
    • Prostaglandin G/H synthase 2 precursor
    • Prostaglandin G/H synthase and cyclooxygenase
    • Prostaglandin H2 synthase 2
    • Prostaglandin-endoperoxide synthase 2
    • prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
    • PTGS2
    • ptgs2a
    • TIS10
    • TIS10 protein
    • unp1239
    • wu:fj02a10
    see all
  • 機能Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.
  • パスウェイLipid metabolism; prostaglandin biosynthesis.
  • 配列類似性Belongs to the prostaglandin G/H synthase family.
    Contains 1 EGF-like domain.
  • 翻訳後修飾S-nitrosylation by NOS2 (iNOS) activates enzme activity. S-nitrosylation may take place on different Cys residues in addition to Cys-561.
  • 細胞内局在Microsome membrane. Endoplasmic reticulum membrane.
  • Information by UniProt

Recombinant human COX2 / Cyclooxygenase 2 protein 画像

  • Standard curve for COX2 / Cyclooxygenase 2 (Analyte: ab58868); dilution range 1pg/ml to 1µg/ml using Capture Antibody ab90345 at 1µg/ml and Detector Antibody ab15191 at 0.5µg/ml.

Recombinant human COX2 / Cyclooxygenase 2 protein (ab58868) 使用論文

ab58868 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"