製品の概要

  • 製品名Recombinant Human COPZ1 protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P61923
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMEALILEPSLYTVKAILILDNDGDRLFAKY YDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVI GSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVD GGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR
    • 分子量22 kDa including tags
    • 領域1 to 177
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab107148 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度> 95 % SDS-PAGE.
    ab107148 is purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0

関連情報

  • 別名
    • 5930435A22Rik
    • AA407760
    • CGI 120
    • Coatomer protein complex subunit zeta 1
    • Coatomer subunit zeta 1
    • Coatomer subunit zeta-1
    • COPZ
    • COPZ 1
    • COPZ1
    • COPZ1_HUMAN
    • D4Ertd360e
    • HSPC181
    • MGC118060
    • Zeta 1 coat protein
    • zeta 1 COP
    • zeta COP
    • Zeta-1 COP
    • Zeta-1-coat protein
    • Zeta1 COP
    see all
  • 機能The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
    The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
  • 配列類似性Belongs to the adaptor complexes small subunit family.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Cytoplasm. Golgi apparatus membrane. Cytoplasmic vesicle > COPI-coated vesicle membrane. The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
  • Information by UniProt

Recombinant Human COPZ1 protein 画像

  • 15% SDS-PAGE showing ab107148 (3µg).

Recombinant Human COPZ1 protein (ab107148) 使用論文

ab107148 has not yet been referenced specifically in any publications.

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