由来 Baculovirus infected Sf9 cells
配列 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIR EISLLKELRH
FP KWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDN QIKKM
領域 1 to 297
タグ GST tag N-Terminus 特性
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
備考 This protein is inactive. CDK1 is activated by its counterpart Cyclin (eg. Cyclin A). Since CDK1 is not expressed with Cyclin, the protein is inactive
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 25% Glycerol, 50mM Sodium chloride, 50mM Tris HCl, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
機能 Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
組織特異性 Isoform 2 is found in breast cancer tissues.
配列類似性 Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. Contains 1 protein kinase domain.
Information by UniProt
Recombinant Human CDK1 protein 画像
Recombinant Human CDK1 protein (ab64306) 使用論文
has not yet been referenced specifically in any publications.
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