製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MKHHHHHHASMVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERM EQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQ LRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDS EEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYL VIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTK IKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPG GLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSG LWVPNSKASEAKEGEEAGPGDPLLEAVPKTGDEKDVSV
    • 分子量
      46 kDa including tags
    • 領域
      1 to 378
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab101118 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Western blot

  • 製品の状態
    Lyophilised
  • 備考
    Store lyophilized protein at –20°C. Lyophilized protein is unstable at 4°C and at RT. Lyophilized protein remains stable until the expiry date when stored at –20°C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at –80°C for long term storage. Reconstituted protein can be stored at 4°C for a limited period of time unlike the lyophilized protein; it does not show any change after one week at 4°C. If not stored at –20°C the protein must be reconstituted to remain stable.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50mM Sodium chloride, 20mM Tris, pH 7.5

  • 再構成
    Add deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

関連情報

  • 別名
    • CDC 37
    • Cdc37
    • CDC37 cell division cycle 37 homolog
    • CDC37 cell division cycle 37 S cerevisiae homolog
    • CDC37 cell division cycle 37, S cerevisiae, homolog of
    • Cdc37 homolog
    • CDC37 protein
    • CDC37_HUMAN
    • CDC37A
    • cell division cycle 37
    • Cell division cycle 37 homolog
    • Hsp90 chaperone protein kinase targeting subunit
    • Hsp90 chaperone protein kinase targeting subunit p50Cdc37
    • Hsp90 chaperone protein kinase-targeting subunit
    • Hsp90 co chaperone Cdc37
    • Hsp90 co-chaperone Cdc37
    • p50
    • p50Cdc37
    • S cerevisiae hypothetical protein CDC37
    see all
  • 機能
    Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
  • 配列類似性
    Belongs to the CDC37 family.
  • 翻訳後修飾
    Constitutively sumoylated by UBE2I.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt

画像

  • 14% SDS-PAGE analysis of ab101118
    Lane 1: Molecular weight markers 14, 21, 31, 45, 66, 97 kDa
    Lane 2: ab101118 (reduced and heated, 5µg/lane)
    Lane 3: ab101118 (non-reduced and non-heated, 5µg/lane)

参考文献

ab101118 has not yet been referenced specifically in any publications.

レビューと Q&A

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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