製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P48960
    • 生物種Human
    • 配列KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLE SSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKN GSTTCQCSH
    • 分子量38 kDa including tags
    • 領域421 to 529

特性

Our Abpromise guarantee covers the use of ab114866 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • ADGRE5
    • Adhesion G protein-coupled receptor E5
    • CD 97
    • CD_antigen=CD97
    • CD97
    • CD97 antigen
    • CD97 antigen subunit beta
    • CD97 molecule
    • CD97_HUMAN
    • Leukocyte antigen CD97
    • Seven span transmembrane protein
    • Seven transmembrane helix receptor
    • Seven transmembrane heterodimeric receptor associated with inflammation
    • TM7LN 1
    • TM7LN1
    see all
  • 機能Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration.
  • 組織特異性Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Expressed also abundantly by smooth muscle cells. Expressed in thyroid, colorectal, gastric, esophageal and pancreatic carcinomas too. Expression are increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients with rheumatoid arthritis. Increased expression of CD97 in the synovium is accompagnied by detectable levels of soluble CD97 in the synovial fluid.
  • 配列類似性Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 5 EGF-like domains.
    Contains 1 GPS domain.
  • ドメインThe first two EGF domains mediate the interaction with DAF. A third tandemly arranged EGF domain is necessary for the structural integrity of the binding region.
    Binding to chondroitin sulfate is mediated by the fourth EGF domain.
  • 翻訳後修飾Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.
  • 細胞内局在Cell membrane and Secreted > extracellular space.
  • Information by UniProt

Recombinant Human CD97 protein 画像

  • ab114866 analysed by 12.5% SDS-PAGE and stained with Coomassie Blue.

Recombinant Human CD97 protein (ab114866) 使用論文

ab114866 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"