製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 配列LPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQW SDIEEFCNR
    • 領域38 to 96

特性

Our Abpromise guarantee covers the use of ab80038 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    ELISA

    SDS-PAGE

  • 精製度> 90 % SDS-PAGE.

  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: PBS

  • 再構成Redissolve the powder with 1ml sterile water will restore to the original concentration 1mg/ml.

関連情報

  • 別名
    • CD 55
    • CD55
    • CD55 antigen
    • CD55 Cromer blood group system
    • CD55 molecule
    • CD55 molecule, decay accelerating factor for complement (Cromer blood group)
    • Cd55a
    • Complement decay accelerating factor
    • Complement decay-accelerating factor
    • Complement decay-accelerating factor, GPI-anchored
    • CR
    • CROM
    • Cromer Blood Group antigen
    • Cromer blood group system
    • DAF
    • Daf-GPI
    • DAF_HUMAN
    • Daf1
    • Dcay accelerating factor for complement (CD55, Cromer blood group system)
    • Decay accelarating factor 1, isoform CRA_a
    • Decay accelerating factor (GPI-form)
    • Decay Accelerating Factor for Complement
    • Decay accelerating factor GPI-form
    • Decay accelerating factor soluble-form
    • GPI-DAF
    • TC
    see all
  • 機能This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
  • 組織特異性Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix.
  • 配列類似性Belongs to the receptors of complement activation (RCA) family.
    Contains 4 Sushi (CCP/SCR) domains.
  • ドメインThe first Sushi domain (SCR1) is not necessary for function. SCR2 and SCR4 provide the proper conformation for the active site on SCR3.
  • 翻訳後修飾The Ser/Thr-rich domain is heavily O-glycosylated.
  • 細胞内局在Cell membrane.
  • Information by UniProt

Recombinant Human CD55 protein 画像

  • 20% SDS PAGE gel, Commassie blue staining.

Recombinant Human CD55 protein (ab80038) 使用論文

ab80038 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"