製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      FKIPIEELEDRVFVNCNTSITWVEGTVGTLLSDITRLDLGKRILDPRGIY RCNGTDIYKDKESTVQVHYRMCQSCVELD
    • 分子量
      34 kDa
    • 領域
      22 to 100
    • タグ
      GST tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab112261 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    Western blot

    SDS-PAGE

  • 製品の状態
    Liquid
  • 備考
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione

関連情報

  • 別名
    • CD3 antigen delta subunit
    • CD3 delta
    • CD3-delta
    • CD3d
    • CD3d antigen delta polypeptide (TiT3 complex)
    • CD3d molecule
    • CD3d molecule delta (CD3-TCR complex)
    • CD3D_HUMAN
    • IMD19
    • OKT3 delta chain
    • T cell receptor T3 delta chain
    • T-cell receptor T3 delta chain
    • T-cell surface glycoprotein CD3 delta chain
    • T3D
    see all
  • 機能
    The CD3 complex mediates signal transduction.
  • 関連疾患
    Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T(-)/B(+)/NK(+) SCID) [MIM:608971]. A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. Patients present in infancy recurrent, persistent infections by opportunistic organisms. The common characteristic of all types of SCID is absence of T-cell-mediated cellular immunity due to a defect in T-cell development.
  • 配列類似性
    Contains 1 ITAM domain.
  • 細胞内局在
    Membrane.
  • Information by UniProt

画像

  • ab112261 on a 12.5% SDS-PAGE Stained with Coomassie Blue.

参考文献

ab112261 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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