Recombinant Human CD3 zeta protein (ab112263)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MKWKALFTAAILQAQLPITEAQSFGLLDPKLCYLLDGILFIYGVILTALF LRVKFSRSADAPAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGGKP QRRKNPQEGLYNELQKDKMAEAYSEIGMKGERRRGKGHDGLYQGLSTATK DTYDALHMQALPPR
    • 分子量
      44 kDa including tags
    • 領域
      1 to 164
    • タグ
      GST tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab112263 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    Western blot

    SDS-PAGE

  • 製品の状態
    Liquid
  • 備考
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione

関連情報

  • 別名
    • 4930549J05Rik
    • A430104F18Rik
    • AW552088
    • CD247
    • CD247 antigen
    • Cd247 molecule
    • Cd3
    • CD3 antigen, zeta polypeptide, isoform CRA_b
    • CD3 antigen, zeta subunit
    • CD3-eta
    • CD3H
    • CD3Q
    • Cd3z
    • CD3Z antigen zeta polypeptide (TiT3 complex)
    • CD3Z_HUMAN
    • CD3zeta
    • CD3zeta chain
    • MGC140430
    • T cell receptor T3 zeta chain
    • T cell surface glycoprotein CD3 zeta chain
    • T-cell antigen receptor complex, zeta subunit of CD3
    • T-cell receptor T3 zeta chain
    • T-cell surface glycoprotein CD3 zeta chain
    • T3z
    • TCR zeta chain
    • TCRk
    • TCRZ
    • TCRzeta
    see all
  • 機能
    Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.
  • 関連疾患
    Defects in CD247 are the cause of immunodeficiency due to defect in CD3-zeta (CD3ZID) [MIM:610163]. An immunological deficiency characterized by T-cells impaired immune response to alloantigens, tetanus toxoid and mitogens.
  • 配列類似性
    Belongs to the CD3Z/FCER1G family.
    Contains 3 ITAM domains.
  • ドメイン
    The ITAM domains mediate interaction with SHB.
  • 翻訳後修飾
    Phosphorylated on Tyr residues after T-cell receptor triggering.
  • 細胞内局在
    Membrane.
  • Information by UniProt

画像

  • ab112263 on a 12.5% SDS-PAGE Stained with Coomassie Blue.

参考文献

ab112263 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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