Recombinant Human CD3 zeta protein (ab112263)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P20963
    • 生物種Human
    • 配列MKWKALFTAAILQAQLPITEAQSFGLLDPKLCYLLDGILFIYGVILTALF LRVKFSRSADAPAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGGKP QRRKNPQEGLYNELQKDKMAEAYSEIGMKGERRRGKGHDGLYQGLSTATK DTYDALHMQALPPR
    • 分子量44 kDa including tags
    • 領域1 to 164
    • タグGST tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab112263 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    Western blot

    SDS-PAGE

  • 製品の状態Liquid
  • 備考Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione

関連情報

  • 別名
    • 4930549J05Rik
    • A430104F18Rik
    • AW552088
    • CD247
    • CD247 antigen
    • Cd247 molecule
    • Cd3
    • CD3 antigen, zeta polypeptide, isoform CRA_b
    • CD3 antigen, zeta subunit
    • CD3-eta
    • CD3H
    • CD3Q
    • Cd3z
    • CD3Z antigen zeta polypeptide (TiT3 complex)
    • CD3Z_HUMAN
    • CD3zeta
    • CD3zeta chain
    • MGC140430
    • T cell receptor T3 zeta chain
    • T cell surface glycoprotein CD3 zeta chain
    • T-cell antigen receptor complex, zeta subunit of CD3
    • T-cell receptor T3 zeta chain
    • T-cell surface glycoprotein CD3 zeta chain
    • T3z
    • TCR zeta chain
    • TCRk
    • TCRZ
    • TCRzeta
    see all
  • 機能Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.
  • 関連疾患Defects in CD247 are the cause of immunodeficiency due to defect in CD3-zeta (CD3ZID) [MIM:610163]. An immunological deficiency characterized by T-cells impaired immune response to alloantigens, tetanus toxoid and mitogens.
  • 配列類似性Belongs to the CD3Z/FCER1G family.
    Contains 3 ITAM domains.
  • ドメインThe ITAM domains mediate interaction with SHB.
  • 翻訳後修飾Phosphorylated on Tyr residues after T-cell receptor triggering.
  • 細胞内局在Membrane.
  • Information by UniProt

Recombinant Human CD3 zeta protein 画像

  • ab112263 on a 12.5% SDS-PAGE Stained with Coomassie Blue.

Recombinant Human CD3 zeta protein (ab112263) 使用論文

ab112263 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab112263.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"