The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Shipped at 4°C. Store at -20°C.
Constituents: 0.32% Tris HCl, 0.58% Sodium chloride
Reconstitute with water to desired concentration.
Hyaluronan mediated motility receptor
Hyaluronan-mediated motility receptor (RHAMM)
Intracellular hyaluronic acid-binding protein
Receptor for hyaluronan-mediated motility
Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the focal adhesion kinase occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity.
Expressed in breast cancer cell lines and in normal breast tissue.