製品の概要

  • 製品名Recombinant Human CCDC5 protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q96CS2
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MGSHMEPQEE RETQVAAWLK KIFGDHPIPQ YEVNPRTTEI LHHLSERNRV RDRDVYLVIE DLKQKASEYE SEAKYLQDLL MESVNFSPAN LSSTGSRYLN ALVDSAVALE TKDTSLASFI PAVNDLTSDL FRTKSKSEEI KIELEKLEKN LTATLVLEKC LQEDVKKAEL HLSTERAKVD NRRQNMDFLK AKSEEFRFGI KAAEEQLSAR GMDASLSHQS LVALSEKLAR LKQQTIPLKK KLESYLDLMP NPSLAQVKIE EAKRELDSIE AELTRRVDMM EL
    • 分子量34 kDa including tags
    • 領域1 to 278
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab124590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度> 85 % SDS-PAGE.
    ab124590 is purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.03% DTT, 0.32% Tris HCl, 50% Glycerol, 1.17% Sodium chloride

関連情報

  • 別名
    • Coiled coil domain containing 5 (spindle associated)
    • Coiled coil domain containing protein 5
    • Coiled-coil domain-containing protein 5
    • Enhancer of invasion cluster
    • Enhancer of invasion-cluster
    • HAUS augmin-like complex subunit 1
    • HAUS1
    • HAUS1_HUMAN
    • HEI-C
    • HEIC
    • HsT1461
    see all
  • 機能Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
  • 組織特異性Widely expressed. Expressed in pancreas, kidney, skeletal muscle, liver and heart. Weakly expressed in lung, brain and placenta.
  • 配列類似性Belongs to the HAUS1 family.
  • 細胞内局在Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Cytoplasm > cytoskeleton > spindle pole. Localizes with the spindle poles in mitotic cells. In metaphase, localizes to the mitotic asters and is highly punctate on the microtubule array. During later stages of mitosis, remains on the spindle but is not present at the interzone, and is finally observed at the microtubule bundles proximal to the midbody, clearly excluded from the midbody. In contrast, does not colocalize with the tubulin cytoskeleton in interphase cells. In interphase, localized at the centrosome and diffusely in the cytoplasm.
  • Information by UniProt

Recombinant Human CCDC5 protein 画像

  • 15% SDS-PAGE showing ab124590 (3µg).

Recombinant Human CCDC5 protein (ab124590) 使用論文

ab124590 has not yet been referenced specifically in any publications.

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