製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P16152
    • 生物種Human
    • 配列MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQL QAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADP TPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALKSC SPELQQKFRSETITEEELVGLMNKFVEDTKKGVHQKEGWPSSAYGVTKIG VTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSPEEGAET PVYLALLPPDAEGPHGQFVSEKRVEQW
    • 分子量30 kDa
    • 領域1 to 277

特性

Our Abpromise guarantee covers the use of ab117172 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.
    ab117172 is purified by proprietary chromatographic techniques.
  • 製品の状態Liquid
  • 備考Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Please see notes section.

    pH: 8.50
    Constituents: 0.32% Tris HCl, 10% Glycerol

関連情報

  • 別名
    • 15 hydroxyprostaglandin dehydrogenase [NADP+]
    • 15-hydroxyprostaglandin dehydrogenase [NADP+]
    • Carbonyl reductase [NADPH] 1
    • Carbonyl Reductase 1
    • CBR 1
    • CBR1
    • CBR1_HUMAN
    • CRN
    • NADPH dependent carbonyl reductase 1
    • NADPH-dependent carbonyl reductase 1
    • Prostaglandin 9 ketoreductase
    • Prostaglandin 9-ketoreductase
    • Prostaglandin E(2) 9 reductase
    • Prostaglandin-E(2) 9-reductase
    • SDR21C1
    see all
  • 機能NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
  • 配列類似性Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • 細胞内局在Cytoplasm.
  • Information by UniProt

Recombinant Human CBR1 protein (ab117172) 使用論文

ab117172 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"