Recombinant Human Cardiac Troponin T protein (ab86685)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MSDIEEVVEE YEEEEQEEAA VEEQEEAAEE DAEAEAETEE TRAEEDEEEE EAKEAEDGPM EESKPKPRSF MPNLVPPKIP DGERVDFDDI HRKRMEKDLN ELQALIEAHF ENRKKEEEEL VSLKDRIERR RAERAEQQRI RNEREKERQN RLAEERARRE EEENRRKAED EARKKKALSN MMHFGGYIQK TERKSGKRQT EREKKKKILA ERRKVLAIDH LNEDQLREKA KELWQSIYNL EAEKFDLQEK FKQQKYEINV LRNRINDNQK VSKTRGKAKV TGRWK
    • 領域1 to 285

特性

Our Abpromise guarantee covers the use of ab86685 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 90 % SDS-PAGE.
    ab86685 is purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Preservative: 0.0006% Imidazole
    Constituents: 0.24% Tris HCl, 50% Glycerol, 1.16% Sodium chloride, 0.0017% PMSF, 0.02% DTT

関連情報

  • 別名
    • Cardiac muscle troponin T
    • Cardiomyopathy dilated 1D (autosomal dominant)
    • Cardiomyopathy hypertrophic 2
    • CMD1D
    • CMH2
    • CMPD2
    • cTnT
    • LVNC6
    • MGC3889
    • OTTHUMP00000033864
    • OTTHUMP00000033865
    • OTTHUMP00000033866
    • OTTHUMP00000033867
    • OTTHUMP00000033870
    • OTTHUMP00000218095
    • RCM3
    • TNNT 2
    • TNNT2
    • TNNT2_HUMAN
    • TnTc
    • Troponin T cardiac muscle
    • Troponin T type 2 (cardiac)
    • Troponin T type 2 cardiac
    • Troponin T, cardiac muscle
    • Troponin T2 cardiac
    see all
  • 機能Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
  • 組織特異性Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.
  • 関連疾患Defects in TNNT2 are the cause of cardiomyopathy familial hypertrophic type 2 (CMH2) [MIM:115195]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
    Defects in TNNT2 are the cause of cardiomyopathy dilated type 1D (CMD1D) [MIM:601494]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
    Defects in TNNT2 are the cause of cardiomyopathy familial restrictive type 3 (RCM3) [MIM:612422]. Restrictive cardiomyopathy is a heart disorder characterized by impaired filling of the ventricles with reduced diastolic volume, in the presence of normal or near normal wall thickness and systolic function.
  • 配列類似性Belongs to the troponin T family.
  • Information by UniProt

Recombinant Human Cardiac Troponin T protein 画像

Recombinant Human Cardiac Troponin T protein (ab86685) 使用論文

ab86685 has not yet been referenced specifically in any publications.

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Q1. How can you explain the absence of exon 13 in the protein you are selling?
Here's a link to our protein's description on NCBI: http://www.ncbi.nlm.nih.gov/protein/NP_001001431
For some reason this p...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"