製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q8WVQ1
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MGSHMRPAPG RPPTHNAHNW RLGQAPANWY NDTYPLSPPQ RTPAGIRYRI AVIADLDTES RAQEENTWFS YLKKGYLTLS DSGDKVAVEW DKDHGVLESH LAEKGRGMEL SDLIVFNGKL YSVDDRTGVV YQIEGSKAVP WVILSDGDGT VEKGFKAEWL AVKDERLYVG GLGKEWTTTT GDVVNENPEW VKVVGYKGSV DHENWVSNYN ALRAAAGIQP PGYLIHESAC WSDTLQRWFF LPRRASQERY SEKDDERKGA NLLLSASPDF GDIAVSHVGA VVPTHGFSSF KFIPNTDDQI IVALKSEEDS GRVASYIMAF TLDGRFLLPE TKIGSVKYEG IEFI
    • 分子量41 kDa including tags
    • 領域63 to 401
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab123189 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Mass Spectrometry

    SDS-PAGE

  • 質量分析
    MALDI-TOF
  • 精製度> 90 % SDS-PAGE.
    ab123189 is purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 0.29% Sodium chloride

関連情報

  • 別名
    • Apyrase
    • Apyrase homolog
    • Ca2+ dependent endoplasmic reticulum nucleoside diphosphatase
    • Calcium activated nucleotidase 1
    • CANT 1
    • CANT1
    • CANT1_HUMAN
    • Putative MAPK activating protein PM09
    • Putative MAPK-activating protein PM09
    • Putative NF kappa B activating protein 107
    • Putative NF-kappa-B-activating protein 107
    • SCAN 1
    • SCAN-1
    • SHAPY
    • Soluble Ca activated nucleotidase isozyme 1
    • Soluble calcium activated nucleotidase 1
    • Soluble calcium activated nucleotidase SCAN 1
    • Soluble calcium-activated nucleotidase 1
    see all
  • 機能Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP.
  • 組織特異性Widely expressed.
  • 関連疾患Defects in CANT1 are the cause of Desbuquois dysplasia (DBQD) [MIM:251450]. A chondrodysplasia characterized by severe prenatal and postnatal growth retardation (less than -5 SD), joint laxity, short extremities, progressive scoliosis, round face, midface hypoplasia, prominent bulging eyes. The main radiologic features are short long bones with metaphyseal splay, a 'Swedish key' appearance of the proximal femur (exaggerated trochanter), and advance carpal and tarsal bone age. Two forms of Desbuquois dysplasia are distinguished on the basis of the presence (type 1) or absence (type 2) of characteristic hand anomalies: an extra ossification center distal to the second metacarpal, delta phalanx, bifid distal thumb phalanx, and phalangeal dislocations.
  • 配列類似性Belongs to the apyrase family.
  • 翻訳後修飾N-glycosylated.
  • 細胞内局在Endoplasmic reticulum membrane. Golgi apparatus > Golgi stack membrane. Processed form: Secreted.
  • Information by UniProt

Recombinant Human CANT1 protein 画像

  • 15% SDS-PAGE showing ab123189 (3µg).

Recombinant Human CANT1 protein (ab123189) 使用論文

ab123189 has not yet been referenced specifically in any publications.

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