製品の概要

法規制情報

製品の詳細

  • 由来Recombinant
  • 由来Baculovirus infected Sf9 cells
  • アミノ酸配列
    • 生物種Human

特性

Our Abpromise guarantee covers the use of ab60756 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Functional Studies

    SDS-PAGE

  • 製品の状態Liquid
  • 備考

    ab188554 (CaMKII peptide) can be utilized as a substrate for assessing Kinase activity

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

関連情報

  • 別名
    • Brain Ca(2+) calmodulin dependent protein kinase type 4
    • Brain Ca(2+) calmodulin dependent protein kinase type IV
    • Brain Ca++-calmodulin dependent protein kinase type IV
    • Calcium / calmodulin dependent protein kinase type 4 catalytic chain
    • Calcium / calmodulin dependent protein kinase type IV catalytic chain
    • Calcium/calmodulin dependent protein kinase IV
    • Calcium/calmodulin dependent protein kinase type IV
    • Calcium/calmodulin-dependent protein kinase type IV
    • CAM kinase 4
    • CAM kinase GR
    • CAM kinase IV
    • CAM kinase-GR
    • CaMK 4
    • CAMK GR
    • CaMK IV
    • Camk4
    • CaMKGR
    • IV
    • KCC4_HUMAN
    • MGC36771
    see all
  • 機能Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. May be involved in transcriptional regulation. May be involved in regulation of microtubule dynamics. In vitro, phosphorylates CREB1, CREBBP, PRM2, MEF2A, MEF2D and STMN1/OP18. May be involved in spermatogenesis. May play a role in the consolidation/retention of hippocampus-dependent long-term memory.
  • 組織特異性Expressed in epithelial ovarian cancer tissue.
  • 配列類似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 1 protein kinase domain.
  • 翻訳後修飾Autophosphorylated and phosphorylated by CAMKK1 and CAMKK2 (By similarity). Dephosphorylated by serine/threonine protein phosphatase 2A, probably on Thr-200.
  • 細胞内局在Cytoplasm. Nucleus. Substantial localization in certain neuronal nuclei. In spermatids associated with chromatin and nuclear matrix.
  • Information by UniProt

Recombinant Human CAMKIV protein 画像

  • Sample Kinase Activity Plot.
  • ab60756 on SDS-PAGE, MW ~79kDa.

Recombinant Human CAMKIV protein (ab60756) 使用論文

ab60756 has not yet been referenced specifically in any publications.

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