- 由来Baculovirus infected Sf9 cells
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 生理活性Specific Activity
151 nmol phosphate incorporated into Autocamtide 2 per minute per mg protein at 30ºC for 15 minutes using a final concentration of 50 µM ATP (0.83 µCi/assay).
- 精製度> 90
Purity > 90% as determined by SDS-PAGE and Coomassie blue staining.
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Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- Calcium/calmodulin dependent protein kinase type 1G
- Calcium/calmodulin-dependent protein kinase I-gamma
- Calcium/calmodulin-dependent protein kinase Ig
- 機能Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates transcription factor CREB1.
- 組織特異性Mainly expressed in brain with small amounts in skeletal muscles, kidney, spleen and liver. Strongly expressed in forebrain neocortex, striatum and limbic system.
- 配列類似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Contains 1 protein kinase domain.
- ドメインThe autoinhibitory domain overlaps with the calmodulin binding region and interacts in the inactive folded state with the catalytic domain as a pseudosubstrate.
- 翻訳後修飾May be prenylated on Cys-473.
- 細胞内局在Cytoplasm. Golgi apparatus membrane. Cell membrane.
Information by UniProt
Recombinant human CaMKI gamma protein 画像
Recombinant human CaMKI gamma protein (ab61917) 使用論文
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"