Recombinant Human Calreticulin protein (ab91577)

Submit an Abreview Q&A (1)
Customer reviews and FAQs

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • 生物種
      Human

特性

Our Abpromise guarantee covers the use of ab91577 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    SDS-PAGE

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: Glycerol, Sodium chloride, Tris buffered saline, 5mM Calcium chloride

関連情報

  • 別名
    • Autoantigen RO
    • CALR
    • CALR protein
    • CALR_HUMAN
    • Calregulin
    • Calreticulin
    • cC1qR
    • CRP55
    • CRT
    • CRTC
    • Endoplasmic reticulum resident protein 60
    • Epididymis secretory sperm binding protein Li 99n
    • ERp60
    • FLJ26680
    • grp60
    • HACBP
    • HEL S 99n
    • RO
    • Sicca syndrome antigen A
    • Sicca syndrome antigen A (autoantigen Ro; calreticulin)
    • SSA
    see all
  • 機能
    Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export.
  • 配列類似性
    Belongs to the calreticulin family.
  • ドメイン
    Can be divided into a N-terminal globular domain, a proline-rich P-domain forming an elongated arm-like structure and a C-terminal acidic domain. The P-domain binds one molecule of calcium with high affinity, whereas the acidic C-domain binds multiple calcium ions with low affinity.
    The interaction with glycans occurs through a binding site in the globular lectin domain.
    The zinc binding sites are localized to the N-domain.
    Associates with PDIA3 through the tip of the extended arm formed by the P-domain.
  • 細胞内局在
    Endoplasmic reticulum lumen. Cytoplasm > cytosol. Secreted > extracellular space > extracellular matrix. Cell surface. Also found in cell surface (T cells), cytosol and extracellular matrix. Associated with the lytic granules in the cytolytic T-lymphocytes.
  • Information by UniProt

Recombinant Human Calreticulin protein 画像

  • SDS-PAGE - Calreticulin protein (Human) (ab91577)
    SDS-PAGE - Calreticulin protein (Human) (ab91577)
    SDS-PAGE Analysis of ab91577 stained with Coomassie Blue.
    Lane 1: MW Marker
    Lane 2: 0.5 µg purified Calreticulin
    Lane 3: 1 µg purified Calreticulin
    Lane 4: 2 µg purified Calreticulin
    Lane 5: 5 µg purified Calreticulin
  • Western blot - Calreticulin protein (Human) (ab91577)
    Western blot - Calreticulin protein (Human) (ab91577)
    All lanes : Recombinant Human Calreticulin protein (ab91577) at 1/1000 dilution

    Lane 1 : MW Marker
    Lane 2 : 50ng Calreticulin
    Lane 3 : 100ng Calreticulin

Recombinant Human Calreticulin protein (ab91577) 使用論文

ab91577 has not yet been referenced specifically in any publications.

ab91577 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

Product Wall

ab91577 の abreview を投稿する ab91577 に関する問い合わせをする

1 Abreview or Q&A

10
Votes: Highest First


Inquiry: Regarding your product "Calreticulin protein (Human) (ab91577)", is this the full-length protein? Your website gives an amino acid start and end of '0'.

Thank you for contacting us.


Yes, this is the full length protein. For full length proteins we have left the start and stop amino acids as 0, since there is not a start and stop like there is for a peptide.

I hope this infor...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録