Recombinant Human Calpain 3 protein (ab114576)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P20807-4
    • 生物種Human
    • 配列MHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYE PHQEGEFILRVFSEKRNLSEEVENTISVDRPVKKKKTKPIIFVSDRANSN KELGVDQESEEGKGKTSPDKQKQSPQPQPGSSDQESEEQQQFRNIFKQIA GDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKL NLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQL YDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVL EWLQLTMYA
    • 分子量60 kDa including tags
    • 領域1 to 309

特性

Our Abpromise guarantee covers the use of ab114576 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    ELISA

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • Calcium-activated neutral proteinase 3
    • calpain 3, (p94)
    • Calpain L3
    • Calpain large polypeptide L3
    • Calpain p94
    • calpain p94, large [catalytic] subunit
    • calpain, large polypeptide L3
    • Calpain-3
    • CAN3_HUMAN
    • CANP 3
    • CANP3
    • CANPL3
    • CAPN3
    • LGMD 2A
    • LGMD2
    • LGMD2A
    • Lp82
    • Lp85
    • MGC10767
    • MGC11121
    • MGC14344
    • MGC4403
    • Muscle-specific calcium-activated neutral protease 3
    • muscle-specific calcium-activated neutral protease 3 large subunit
    • nCL-1
    • New calpain 1
    • p94
    see all
  • 機能Calcium-regulated non-lysosomal thiol-protease.
  • 組織特異性Isoform I is skeletal muscle specific.
  • 関連疾患Defects in CAPN3 are the cause of limb-girdle muscular dystrophy type 2A (LGMD2A) [MIM:253600]. LGMD2A is an autosomal recessive degenerative myopathy characterized by progressive symmetrical atrophy and weakness of the proximal limb muscles and elevated serum creatine kinase. The symptoms usually begin during the first two decades of life, and the disease gradually worsens, often resulting in loss of walking ability 10 or 20 years after onset.
  • 配列類似性Belongs to the peptidase C2 family.
    Contains 1 calpain catalytic domain.
    Contains 4 EF-hand domains.
  • 細胞内局在Cytoplasm.
  • Information by UniProt

Recombinant Human Calpain 3 protein 画像

  • ab114576 on a 12.5% SDS-PAGE Stained with Coomassie Blue.

Recombinant Human Calpain 3 protein (ab114576) 使用論文

ab114576 has not yet been referenced specifically in any publications.

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