Recombinant Human Calcium binding protein P22 (ab99141)

製品の概要

  • 製品名
    Recombinant Human Calcium binding protein P22
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMMGSRASTLLRDEELEEIKKETGFSHSQIT RLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFPEGEDQVN FRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDEK ISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKV LEKVDVEQKMSIRFLH
    • 分子量
      25 kDa including tags
    • 領域
      1 to 195
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab99141 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 95 % SDS-PAGE.
    ab99141 was purified by using conventional chromatography.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, pH 7.5

関連情報

  • 別名
    • Calcineurin B homolog
    • Calcineurin B homologous protein
    • Calcineurin homologous protein
    • Calcineurin like EF hand protein 1
    • Calcium binding protein CHP
    • Calcium binding protein p22
    • Calcium-binding protein CHP
    • Calcium-binding protein p22
    • chp
    • CHP1_HUMAN
    • Sid 470
    • Sid470
    • SLC9A1 binding protein
    • SLC9A1BP
    • Wrch2
    see all
  • 機能
    Required for constitutive membrane traffic. Inhibits GTPase-stimulated Na(+)/H(+) exchange. Also inhibits calcineurin phosphatase activity. Required for activity of SLC9A1/NHE1.
  • 組織特異性
    Ubiquitously expressed. Has been found in fetal eye, lung, liver, muscle, heart, kidney, thymus and spleen.
  • 配列類似性
    Contains 4 EF-hand domains.
  • 翻訳後修飾
    Both N-myristoylation and calcium-mediated conformational changes are essential for its function in exocytic traffic.
    Phosphorylated; decreased phosphorylation is associated with an increase in exchange activity. The phosphorylation state may regulate the binding to NHE1.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt

画像

  • 15% SDS-PAGE analysis of 3µg ab99141.

参考文献

ab99141 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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