製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      APVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPL EFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGN
    • 分子量
      37 kDa including tags
    • 領域
      25 to 124

関連製品

特性

Our Abpromise guarantee covers the use of ab116784 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    SDS-PAGE

    ELISA

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • CA 12
    • CA XII
    • CA-XII
    • CA12
    • CAH12_HUMAN
    • Carbonate dehydratase XII
    • Carbonic anhydrase 12
    • Carbonic anhydrase XII
    • Carbonic dehydratase
    • CAXII
    • FLJ20151
    • HsT18816
    • T18816
    • Tumor antigen HOM RCC 3.1.3
    • Tumor antigen HOM-RCC-3.1.3
    see all
  • 機能
    Reversible hydration of carbon dioxide.
  • 組織特異性
    Highly expressed in colon, kidney, prostate, intestine and activated lymphocytes. Expressed at much higher levels in the renal cell cancers than in surrounding normal kidney tissue. Moderately expressed in pancreas, ovary and testis.
  • 関連疾患
    Defects in CA12 are the cause of hyperchlorhidrosis isolated (HCHLH) [MIM:143860]. HCHLH is a disorder characterized by excessive sweating and increased sweat chloride levels. Affected individuals suffer from episodes of hyponatremic dehydration and report increased amounts of visible salt precipitates in sweat.
  • 配列類似性
    Belongs to the alpha-carbonic anhydrase family.
  • 細胞内局在
    Membrane.
  • Information by UniProt

Recombinant Human CA12 protein 画像

  • ab116784 analysed on a 12.5% SDS-PAGE Stained with Coomassie Blue.

Recombinant Human CA12 protein (ab116784) 使用論文

ab116784 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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