Recombinant Human Brachyury / Bry protein (ab114235)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号O15178
    • 生物種Human
    • 配列MSSPGTESAGKSLQYRVDHLLSAVENELQAGSEKGDPTERELRVGLEESE LWLRFKELTNEMIVTKNGRRMFPVL KVNVSGLDPNAMYSFLLDFVAAD NHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKL TN KLNGGGQIMLNSLHKYEPRIHIVRVGDPQRMITSHCFPETQFIAVT AYQNEEITALKIKYNPFAKAFLDAKERSD HKEMMEEPGDSQQPGYSQS YSDNSPACLSMLQSHDNWSSLGMPAHPSMLPVSHNASPPTSSSQYPSLWS VSNGAV TPGSQAAAVSNGLGAQFFRGSPAHYTPLTHPVSAPSSSGSPL YEGAAAATDIVDSQYDAAAQGRLIASWTPVSPP SM
    • 分子量68 kDa including tags
    • 領域1 to 377

特性

Our Abpromise guarantee covers the use of ab114235 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • BRAC_HUMAN
    • Brachyury homolog
    • Brachyury protein
    • Bry
    • MGC104817
    • Protein T
    • SAVA
    • T
    • T brachyury homolog
    • T brachyury transcription factor
    • T Protein
    • T, brachyury homolog (mouse)
    • TFT
    • Transcription factor T
    see all
  • 機能Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site.
  • 関連疾患Genetic variations in T are associated with susceptibility to neural tube defects (NTD) [MIM:182940]. NTD are common congenital malformations. Spina bifida, which results from malformations in the caudal region of the neural tube, is compatible with life but associated with significant morbidity, including lower limb paralysis.
    T is involved in susceptibility to the development of chordoma (CHDM) [MIM:215400]. Chordomas are rare, clinically malignant tumors derived from notochordal remnants. They occur along the length of the spinal axis, predominantly in the sphenooccipital, vertebral and sacrococcygeal regions. They are characterized by slow growth, local destruction of bone, extension into adjacent soft tissues and rarely, distant metastatic spread. Note=Susceptibility to development of chordomas is due to a T gene duplication.
  • 配列類似性Contains 1 T-box DNA-binding domain.
  • 細胞内局在Nucleus.
  • Information by UniProt

Recombinant Human Brachyury / Bry protein 画像

  • 12.5% SDS-PAGE showing ab114235 at approximately 67.54kDa stained with Coomassie Blue.

Recombinant Human Brachyury / Bry protein (ab114235) 使用論文

ab114235 has not yet been referenced specifically in any publications.

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