Full length protein
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The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0
- 2,3-bisphosphoglycerate mutase
- 2,3-bisphosphoglycerate mutase, erythrocyte
Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 220.127.116.11) and phosphatase (EC 18.104.22.168) activities.
Defects in BPGM are the cause of bisphosphoglycerate mutase deficiency (BPGMD) [MIM:222800]. A disease characterized by hemolytic anemia, splenomegaly, cholelithiasis and cholecystitis.
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Glycation of Lys-159 in diabetic patients inactivates the enzyme.
Information by UniProt
has not yet been referenced specifically in any publications.
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