Recombinant Human Bim protein (ab112387)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQDRSPAPMSC DKSTQTPSPPCQAFNHYLSAMVVILEDIGDLSLCFGFIFTGLDLYGHHHS QDTEQLNHKDFS
    • 分子量
      39 kDa including tags
    • 領域
      1 to 112

特性

Our Abpromise guarantee covers the use of ab112387 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    ELISA

    Western blot

    Other

  • 製品の状態
    Liquid
  • 備考
    Best to use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione
    Note: Glutathione is reduced

関連情報

  • 別名
    • BCL2 like 11
    • B2L11_HUMAN
    • BAM
    • Bcl 2 interacting protein Bim
    • Bcl 2 related ovarian death agonist
    • Bcl-2-like protein 11
    • BCL2 interacting mediator of cell death
    • BCL2 like 11 (apoptosis facilitator)
    • BCL2 like protein 11
    • Bcl2-interacting mediator of cell death
    • Bcl2-L-11
    • Bcl2l11
    • BIM
    • BIM alpha6
    • BIM beta6
    • BIM beta7
    • BimEL
    • BimL
    • BOD
    see all
  • 機能
    Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis.
  • 組織特異性
    Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are ubiquitously expressed with a tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney.
  • 配列類似性
    Belongs to the Bcl-2 family.
  • ドメイン
    The BH3 motif is required for Bcl-2 binding and cytotoxicity.
  • 細胞内局在
    Mitochondrion and Endomembrane system. Associated with intracytoplasmic membranes.
  • Information by UniProt

Recombinant Human Bim protein 画像

  • 12.5% SDS-PAGE analysis of ab112387. Stained with Coomassie Blue

Recombinant Human Bim protein (ab112387) 使用論文

ab112387 has not yet been referenced specifically in any publications.

Product Wall

This product is Human Bim full-length ORF ( NP_996885.1, 1 a.a. - 112 a.a.) recombinant protein with a proprietary tag. Please contact our scientific support group for more information regarding this tag. We have not done any tests for enzymatic acti...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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