Recombinant Human Bile salt-activated lipase protein (ab114625)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      GLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHR ANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRP
    • 分子量
      37 kDa including tags
    • 領域
      378 to 477

特性

Our Abpromise guarantee covers the use of ab114625 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

関連情報

  • 別名
    • BAL
    • Bile salt-stimulated lipase
    • BSDL
    • BSSL
    • Bucelipase
    • Carboxyl ester lipase
    • Carboxyl ester lipase (bile salt stimulated lipase)
    • CEase
    • CEL
    • CELL
    • Cholesterol esterase
    • FAP
    • FAPP
    • Fetoacinar pancreatic protein
    • LIPA
    • Lysophospholipase, pancreatic
    • MODY8
    • Pancreatic lysophospholipase
    • Sterol esterase
    see all
  • 関連性
    Defects in Bile salt activated lipase (CEL) are a cause of maturity onset diabetes of the young type 8 with exocrine dysfunction (MODY8) [MIM:609812], also known as diabetes and pancreatic exocrine dysfunction (DPED). MODY [MIM:606391] is an autosomal dominant form of diabetes mellitus. The pancreas serves both endocrine and exocrine functions. The endocrine cells are found in the islets of Langerhans. They synthesize insulin and other hormones, and are involved in the pathogenesis of diabetes mellitus. The exocrine cells produce bicarbonate and digestive enzymes and are involved in the pathogenesis of pancreatic malabsorption. The localization of the islets within exocrine pancreatic tissue is suggestive of an interdependency and cross talk between these two cell populations in their normal and in their abnormal function.
  • 細胞内局在
    Cytoplasmic and Nuclear

画像

  • ab114625 analysed on a 12.5% SDS-PAGE stained with Coomassie Blue.

参考文献

ab114625 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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