Recombinant human beta 2 Defensin protein (ab9872)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P
    • 分子量
      4 kDa
    • 領域
      24 to 64

関連製品

特性

Our Abpromise guarantee covers the use of ab9872 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Functional Studies

    SDS-PAGE

  • エンドトキシン・レベル
    < 0.100 Eu/µg
  • 製品の状態
    Lyophilised
  • 備考

    Beta 2 Defensin protein is expressed as the C-terminal portion of precursors and is released by proteolytic cleavage of a signal sequence (aa 1-23).

    The biological activity of this product is determined by its ability to chemoattract immature human dendritic cells using a concentration range of 10.0-100.0 ng/ml.

     

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    n/a

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • BD 2
    • BD-2
    • BD2
    • beta 2
    • Beta defensin 2
    • Beta defensin 4B
    • Beta-defensin 2
    • Beta-defensin 4A
    • DEF B2
    • DEF B4
    • DEFB 102
    • DEFB 2
    • DEFB 4
    • DEFB102
    • DEFB2
    • DEFB2, formerly
    • DEFB4
    • DEFB4, formerly
    • DEFB4B
    • DEFB4P
    • Defensin
    • Defensin beta 2
    • Defensin, beta 4
    • Defensin, beta 4, pseudogene
    • Defensin, beta 4A
    • Defensin, beta 4B
    • Defensin, beta, 2, formerly
    • Defensin, beta, 4, formerly
    • DFB4A_HUMAN
    • HBD 2
    • hBD-2
    • HBD2
    • mBD-2
    • SAP 1
    • SAP1
    • Skin antimicrobial peptide 1
    • Skin-antimicrobial peptide 1
    see all
  • 機能
    Has antibacterial activity.
  • 組織特異性
    Expressed in the skin and respiratory tract.
  • 配列類似性
    Belongs to the beta-defensin family. LAP/TAP subfamily.
  • 細胞内局在
    Secreted.
  • Information by UniProt

参考文献

ab9872 has not yet been referenced specifically in any publications.

レビューと Q&A

Thank you for your enquiry.

The datasheet for ab9872 states the following, and I can confirm this is regrettably not a full length protein (full length protein is over64 amino acids):

Recombinant Human BD-2 is a 4.3 kDa protein co...

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Thank you for sending along the dot blots and additional information. We really appreciate the extra troubleshootingeffort.

Here are my thoughts:

1. In general it looks like the antibodies are able to detect Defensin in the chorioam...

Read More

Thank you for contacting Abcam Technical Team and for taking the time to provide some useful details of the experiments. I am very sorry to hear that your customer is are having problems with 8 of our products.  Special thanks for collecting the troubl...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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