製品の概要

  • 製品名Recombinant Human BAPX1 protein
  • タンパク質長Protein fragment

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号p78367
    • 生物種Human
    • 配列RLFGERDAGALGGAEDSLLASPAGTRTAAGRTAESPEGWDSDSALSEENE SRRRCADAR
    • 分子量32 kDa including tags
    • 領域53 to 111

特性

Our Abpromise guarantee covers the use of ab114496 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • Bagpipe homeobox 1
    • Bagpipe homeobox homolog 1
    • Bagpipe homeobox protein homolog 1
    • Bagpipe homeobox, Drosophila, homolog of, 1
    • BAPX 1
    • Homeobox protein NK-3 homolog B
    • Homeobox protein Nkx 3.2
    • Homeobox protein Nkx-3.2
    • MGC138171
    • NK3 homeobox 2
    • NKX3 2
    • NKX3-2
    • NKX3.2
    • NKX3.2, mouse, homolog of
    • NKX32_HUMAN
    • NKX3B
    • OTTHUMP00000115816
    • SMMD
    see all
  • 機能Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus.
  • 組織特異性Expressed at highest levels in cartilage, bone (osteosarcoma) and gut (small intestine and colon), whereas moderate expression is seen in trachea and brain. Expressed in visceral mesoderm and embryonic skeleton.
  • 関連疾患Defects in NKX3-2 are the cause of spondylo-megaepiphyseal-metaphyseal dysplasia (SMMD) [MIM:613330]. It is a skeletal dysplasia characterized by disproportionate short stature with a short and stiff neck and trunk, relatively long limbs that may show flexion contractures of the distal joints, delayed and impaired ossification of the vertebral bodies, the presence of large epiphysea ossification centers and wide growth plates in the long tubular bones and numerous pseudoepiphyses of the short tubular bones in hands and feet.
  • 配列類似性Belongs to the NK-3 homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 細胞内局在Nucleus.
  • Information by UniProt

Recombinant Human BAPX1 protein 画像

  • ab114496 analysed by 12.5% SDS-PAGE and stained with Coomassie Blue.

Recombinant Human BAPX1 protein (ab114496) 使用論文

ab114496 has not yet been referenced specifically in any publications.

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