製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q9Y275
    • 生物種Human
    • 配列AVQGPEETVTQDCLQLIADSETPTIQKGSYTFVPWLLSFKRGSALEEKEN KILVKETGYFFIYGQV LYTDKTYAMGHLIQRKKVHVFGDELSLVTLFR CIQNMPETLPNNSCYSAGIAKLEEGDELQLAIP RENAQISLDGDVTFF GALKLL
    • 領域134 to 285
    • 配列の追加情報Soluble form.

特性

Our Abpromise guarantee covers the use of ab50087 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性Biological activity determined by a mouse splenocyte survival assay. The expected ED50 for this effect is 0.5 - 2 µg/ml.
  • アプリケーション

    Functional Studies

    SDS-PAGE

  • エンドトキシン・レベル< 0.100 Eu/µg
  • 精製度> 95 % SDS-PAGE.
    Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成Reconstitute to 1mg/ml with distilled water.

関連情報

  • 別名
    • ApoL related ligand TALL 1
    • B cell Activating Factor
    • B lymphocyte stimulator
    • B-cell-activating factor
    • BAFF
    • BLyS
    • CD 257
    • CD257
    • CD257 antigen
    • Delta BAFF
    • Dendritic cell derived TNF like molecule
    • Dendritic cell-derived TNF-like molecule
    • DTL
    • DTL precursor
    • PRO738
    • soluble form
    • TALL 1
    • TALL-1
    • TALL1
    • THANK
    • TN13B_HUMAN
    • TNF and APOL related leukocyte expressed ligand 1
    • TNF homolog that activates apoptosis
    • TNF homolog that activates apoptosis NKFB and JNK.
    • TNF- and APOL-related leukocyte expressed ligand 1
    • TNFSF13B
    • TNFSF20
    • Tumor necrosis factor (ligand) superfamily member 13b
    • Tumor necrosis factor ligand superfamily member 13b
    • Tumor necrosis factor ligand superfamily member 20
    • Tumor necrosis factor like protein ZTNF4
    • Tumor necrosis factor superfamily member 13B
    • UNQ401
    • ZTNF4
    see all
  • 機能Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B-and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.
  • 組織特異性Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T-cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas.
  • 配列類似性Belongs to the tumor necrosis factor family.
  • 翻訳後修飾The soluble form derives from the membrane form by proteolytic processing.
    N-glycosylated.
  • 細胞内局在Secreted and Cell membrane.
  • Information by UniProt

Recombinant human BAFF protein (ab50087) 使用論文

ab50087 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab50087.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"