製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MDAATLTYDT LRFAEFEDFP ETSEPVWILG RKYSIFTEKD EILSDVASRL WFTYRKNFPA IGGTGPTSDT GWGCMLRCGQ MIFAQALVCR HLGRDWRWTQ RKRQPDSYFS VLNAFIDRKD SYYSIHQIAQ MGVGEGKSIG QWYGPNTVAQ VLKKLAVFDT WSSLAVHIAM DNTVVMEEIR RLCRTSVPCA GATAFPADSD RHCNGFPAGA EVTNRPSPWR PLVLLIPLRL GLTDINEAYV ETLKHCFMMP QSLGVIGGKP NSAHYFIGYV GEELIYLDPH TTQPAVEPTD GCFIPDESFH CQHPPCRMSI AELDPSIAVG FFCKTEDDFN DWCQQVKKLS LLGGALPMFE LVEQQPSHLA CPDVLNLSLD SSDVERLERF FDSEDEDFEI LSLLEHHHHH H
    • 分子量
      45 kDa including tags
    • 領域
      1 to 393
    • タグ
      His tag C-Terminus

特性

Our Abpromise guarantee covers the use of ab123195 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 90 % SDS-PAGE.
    ab123195 is purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.002% PMSF, 0.02% DTT, 0.32% Tris HCl, 20% Glycerol

関連情報

  • 別名
    • APG4 autophagy 4 homolog B
    • APG4B
    • ATG4 autophagy related 4 homolog B (S. cerevisiae)
    • ATG4B
    • ATG4B_HUMAN
    • AUT like 1 cysteine endopeptidase
    • AUT-like 1 cysteine endopeptidase
    • AUTL1
    • Autophagin 1
    • Autophagin-1
    • Autophagy related 4B cysteine peptidase
    • Autophagy related cysteine endopeptidase 1
    • Autophagy related protein 4 homolog B
    • Autophagy-related cysteine endopeptidase 1
    • Autophagy-related protein 4 homolog B
    • Cysteine protease ATG4B
    • hAPG4B
    • MGC1353
    see all
  • 機能
    Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
  • 組織特異性
    Mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas.
  • 配列類似性
    Belongs to the peptidase C54 family.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt

画像

  • 15% SDS-PAGE showing ab123195 (3µg).

参考文献

ab123195 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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