製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 配列MSDDKPFLCT APGCGQRFTN EDHLAVHKHK HEMTLKFGPA RNDSVIVADQ TPTPTRFLKN CEEVGLFNEL ASPFENEFKK ASEDDIKKMP LDLSPLATPI IRSKIEEPSV VETTHQDSPL PHPESTTSDE KEVPLAQTAQ PTSAIVRPAS LQVPNVLLTS SDSSVIIQQA VPSPTSSTVI TQAPSSNRPI VPVPGPFPLL LHLPNGQTMP VAIPASITSS NVHVPAAVPL VRPVTMVPSV PGIPGPSSPQ PVQS
    • 領域1 to 254

特性

Our Abpromise guarantee covers the use of ab43598 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Functional Studies

  • 製品の状態Liquid
  • 備考

    ab43598 (Human ATF2 protein fragment) can be utilized as a substrate for ab60304 (Active mouse JNK1 full length protein)

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5

関連情報

  • 別名
    • Activating transcription factor 2
    • Activating transcription factor 2 splice variant ATF2 var2
    • ATF 2
    • Atf-2
    • Atf2
    • ATF2 protein
    • ATF2_HUMAN
    • cAMP Response Element Binding Protein 2
    • cAMP response element binding protein CRE BP1
    • cAMP response element-binding protein CRE-BP1
    • cAMP responsive element binding protein 2, formerly
    • cAMP-dependent transcription factor ATF-2
    • cAMP-responsive element-binding protein 2
    • CRE BP1
    • CRE-BP
    • CREB 2
    • CREB-2
    • CREB2
    • CREBP1
    • Cyclic AMP dependent transcription factor ATF 2
    • Cyclic AMP-dependent transcription factor ATF-2
    • Cyclic AMP-responsive element-binding protein 2
    • D130078H02Rik
    • D18875
    • HB 16
    • HB16
    • Histone acetyltransferase ATF2
    • MGC105211
    • MGC105222
    • MGC111558
    • MGC142504
    • mXBP
    • MXBP protein
    • Tg(Gzma-Klra1)7Wum
    • TREB 7
    • TREB7
    see all
  • 機能Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex.
  • 組織特異性Abundant expression seen in the brain.
  • 配列類似性Belongs to the bZIP family. ATF subfamily.
    Contains 1 bZIP domain.
    Contains 1 C2H2-type zinc finger.
  • 翻訳後修飾Phosphorylation of Thr-69 and Thr-71 by MAPK14 causes increased transcriptional activity. Also phosphorylated and activated by JNK.
  • 細胞内局在Nucleus.
  • Information by UniProt

Recombinant Human ATF2 protein (ab43598) 使用論文

ab43598 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab43598.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"