製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P00966
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMSSKGSVVLAYSGGLDTSCILVWLKEQGYD VIAYLANIGQKEDFEEARKKALKLGAKKVFIEDVSREFVEEFIWPAIQSS ALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATGKGNDQVRFEL SCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKG VPVKVTNVKDGTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRG IYETPAGTILYHAHLDIEAFTMDREVRKIKQGLGLKFAELVYTGFWHSPE CEFVRHCIAKSQERVEGKVQVSVLKGQVYILGRESPLSLYNEELVSMNVQ GDYEPTDATGFININSLRLKEYHRLQSKVTAK
    • 分子量49 kDa including tags
    • 領域1 to 412
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab116472 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 90 % SDS-PAGE.
    ab116472 is purified by proprietary chromatographic techniques.
  • 製品の状態Liquid
  • 備考although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride, 0.02% DTT, 20% Glycerol

関連情報

  • 別名
    • Argininosuccinate synthase
    • Argininosuccinate synthase 1
    • Argininosuccinate synthetase 1
    • ASS
    • Ass-1
    • ass1
    • ASSA
    • ASSY_HUMAN
    • Citrulline aspartate ligase
    • Citrulline--aspartate ligase
    • CTLN1
    see all
  • パスウェイAmino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.
    Nitrogen metabolism; urea cycle; (N(omega)-L-arginino)succinate from L-aspartate and L-citrulline: step 1/1.
  • 関連疾患Defects in ASS1 are the cause of citrullinemia type 1 (CTLN1) [MIM:215700]. Citrullinemia belongs to the urea cycle disorders. It is an autosomal recessive disease characterized primarily by elevated serum and urine citrulline levels. Ammonia intoxication is another manifestation. CTLN1 usually manifests in the first few days of life. Affected infants appear normal at birth, but as ammonia builds up in the body they present symptoms such as lethargy, poor feeding, vomiting, seizures and loss of consciousness. Less commonly, a milder CTLN1 form can develop later in childhood or adulthood.
  • 配列類似性Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  • Information by UniProt

Recombinant Human ASS1 protein (ab116472) 使用論文

ab116472 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab116472.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"