製品の概要

  • 製品名Recombinant Human ASPA protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P45381
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MGSMTSCHIAEEH IQKVAIFGGT HGNELTGVFL VKHWLENGAE IQRTGLEVKP FITNPRAVKK CTRYIDCDLN RIFDLENLGK KMSEDLPYEV RRAQEINHLF GPKDSEDSYD IIFDLHNTTS NMGCTLILED SRNNFLIQMF HYIKTSLAPL PCYVYLIEHP SLKYATTRSI AKYPVGIEVG PQPQGVLRAD ILDQMRKMIK HALDFIHHFN EGKEFPPCAI EVYKIIEKVD YPRDENGEIA AIIHPNLQDQ DWKPLHPGDP MFLTLDGKTI PLGGDCTVYP VFVNEAAYYE KKEAFAKTTK LTLNAKSIRC CLH
    • 分子量38 kDa including tags
    • 領域1 to 313
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab123155 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Mass Spectrometry

    SDS-PAGE

  • 質量分析
    MALDI-TOF
  • 精製度> 90 % SDS-PAGE.
    ab123155 was purified by using conventional chromatography.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.002% PMSF, 0.02% DTT, 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

関連情報

  • 別名
    • ACY 2
    • ACY-2
    • ACY2
    • ACY2_HUMAN
    • Aminoacylase 2
    • Aminoacylase-2
    • Aminoacylase2
    • ASP
    • ASPA
    • Aspartoacylase
    • Aspartoacylase (aminoacylase 2, Canavan disease)
    • Aspartoacylase (Canavan disease)
    • NUR 7
    • NUR7
    • OTTMUSP00000006437
    • RP23-213I10.1
    • Small lethargic
    see all
  • 機能Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids.
  • 組織特異性Brain white matter, skeletal muscle, kidney, adrenal glands, lung and liver.
  • 関連疾患Defects in ASPA are the cause of Canavan disease (CAND) [MIM:271900]; also known as spongy degeneration of the brain. CAND is a rare neurodegenerative condition of infancy or childhood characterized by white matter vacuolization and demeylination that gives rise to a spongy appearance. The clinical features are onset in early infancy, atonia of neck muscles, hypotonia, hyperextension of legs and flexion of arms, blindness, severe mental defect, megalocephaly, and death by 18 months on the average.
  • 配列類似性Belongs to the AspA/AstE family. Aspartoacylase subfamily.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt

Recombinant Human ASPA protein 画像

  • 15% SDS-PAGE analysis of ab123155 (3 µg).

Recombinant Human ASPA protein (ab123155) 使用論文

ab123155 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"