製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • 生物種
      Human
    • 配列
      MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMAKV QVNNVVVLDN PSPFYNPFQF EITFECIEDL SEDLEWKIIY VGSAESEEYD QVLDSVLVGP VPAGRHMFVF QADAPNPGLI PDADAVGVTV VLITCTYRGQ EFIRVGYYVN NEYTETELRE NPPVKPDFSK LQRNILASNP RVTRFHINWE DNTEKLEDAE SSNPNLQSLL STDALPSASK GWSTSENSLN VMLESHMDCM

特性

Our Abpromise guarantee covers the use of ab84211 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度
    > 90 % SDS-PAGE.
    ab84211 is purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • 備考
    Endotoxin Level: < 1.0 EU per 1 µg of protein (determined by LAL method).
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0

関連情報

  • 別名
    • Anti silencing function 1A
    • Anti-silencing function protein 1 homolog A
    • ASF1 anti silencing function 1 homolog A
    • ASF1 anti silencing function 1 homolog A (S. cerevisiae)
    • asf1a
    • ASF1A_HUMAN
    • CCG1 interacting factor A
    • CCG1-interacting factor A
    • CGI 98
    • CIA
    • hAsf1
    • hAsf1a
    • hCIA
    • Histone chaperone ASF1A
    • HSPC146
    see all
  • 機能
    Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
  • 組織特異性
    Ubiquitously expressed.
  • 配列類似性
    Belongs to the ASF1 family.
  • 翻訳後修飾
    Phosphorylated by TLK1 and TLK2. Highly phosphorylated in S-phase and at lower levels in M-phase.
  • 細胞内局在
    Nucleus.
  • Information by UniProt

画像

  • 15% SDS-PAGE showing ab84211 at approximately 27kDa (3µg).

参考文献

ab84211 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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