製品の概要

  • 製品名Recombinant Human ASAH1 protein
  • タンパク質長Protein fragment

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号Q13510
    • 生物種Human
    • 配列PPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRWHELMLDKAPMLK VIVNSLKNMINTFVPSGKVMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTD
    • 分子量37 kDa including tags
    • 領域25 to 124

関連製品

特性

Our Abpromise guarantee covers the use of ab114948 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • AC
    • ACDase
    • Acid CDase
    • Acid ceramidase
    • Acid ceramidase precursor
    • Acid ceramidase subunit beta
    • Acylsphingosine deacylase
    • ASAH
    • ASAH 1
    • ASAH1
    • ASAH1_HUMAN
    • FLJ21558
    • FLJ22079
    • N acylsphingosine amidohydrolase
    • N acylsphingosine amidohydrolase (acid ceramidase) 1
    • N acylsphingosine amidohydrolase 1
    • N-acylsphingosine amidohydrolase
    • N-acylsphingosine deacylase
    • PHP
    • PHP32
    • Putative 32 kDa heart protein
    • SMAPME
    see all
  • 機能Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
  • 組織特異性Broadly expressed with highest expression in heart.
  • 関連疾患Defects in ASAH1 are the cause of Farber lipogranulomatosis (FL) [MIM:228000]; also known as Farber disease (FD). This sphingolipid disease is characterized by subcutaneous lipid-loaded nodules, excruciating pain in the joints and extremities, marked accumulation of ceramide in lysosomes, and death by three years of age.
  • 配列類似性Belongs to the acid ceramidase family.
  • 細胞内局在Lysosome.
  • Information by UniProt

Recombinant Human ASAH1 protein 画像

  • 12.5% SDS-PAGE showing ab114948 at approximately 36.63kDa.
    Stained with Coomassie Blue.

Recombinant Human ASAH1 protein (ab114948) 使用論文

ab114948 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"