製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMGSHMLRPGDCEVCISYLGRFYQDLKDRDV TFSPATIENELIKFCREARGKENRLCYYIGATDDAATKIINEVSKPLAHH IPVEKICEKLKKKDSQICELKYDKQIDLSTVDLKKLRVKELKKILDDWGE TCKGCAEKSDYIRKINELMPKYAPKAASARTDL
    • 分子量
      21 kDa including tags
    • 領域
      25 to 182
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab124557 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 90 % SDS-PAGE.
    Purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride

関連情報

  • 別名
    • Arginine rich mutated in early stage tumors
    • Arginine rich protein
    • Arginine-rich protein
    • ARMET
    • ARMET protein
    • ARP
    • Manf
    • MANF_HUMAN
    • Mesencephalic astrocyte derived neurotrophic factor
    • Mesencephalic astrocyte-derived neurotrophic factor
    • MGC142148
    • MGC142150
    • Protein ARMET
    see all
  • 機能
    Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
  • 配列類似性
    Belongs to the ARMET family.
  • ドメイン
    The N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response.
  • 翻訳後修飾
    May contain sialic acid residues.
  • 細胞内局在
    Secreted.
  • Information by UniProt

画像

  • 15% SDS-PAGE analysis of 3 µg of ARMET protein (ab124557).

参考文献

ab124557 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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