製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHL KATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWAS YSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEV LECVSLVELTSLKGREKLAPVPFFSLLQYE
    • 分子量
      20 kDa including tags
    • 領域
      1 to 180

特性

Our Abpromise guarantee covers the use of ab116469 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度
    > 90 % SDS-PAGE.
    ab116469 is purified by proprietary chromatographic techniques.
  • 製品の状態
    Liquid
  • 備考
    Although stable 4°C for 4 weeks, ab116469 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.02% DTT, 10% Glycerol

関連情報

  • 別名
    • Adenine phosphoribosyltransferase
    • AMP
    • AMP diphosphorylase
    • AMP pyrophosphorylase
    • APRT
    • APT_HUMAN
    • DKFZp686D13177
    • MGC125856
    • MGC125857
    • MGC129961
    • Transphosphoribosidase
    see all
  • 機能
    Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  • パスウェイ
    Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.
  • 関連疾患
    Defects in APRT are the cause of adenine phosphoribosyltransferase deficiency (APRTD) [MIM:102600]; also known as 2,8-dihydroxyadenine urolithiasis. An enzymatic deficiency that can lead to urolithiasis and renal failure. Patients have 2,8-dihydroxyadenine (DHA) urinary stones.
  • 配列類似性
    Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt

参考文献

ab116469 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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