Recombinant Human Annexin-2/ANXA2 protein (ab93005)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 0.250 Eu/ml
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE, MS, WB, ELISA
製品の詳細
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製品名
Recombinant Human Annexin-2/ANXA2 protein
Annexin-2/ANXA2 タンパク質・ペプチド 製品一覧 -
精製度
> 95 % SDS-PAGE.
Purified by 6xHis tag / Immobilized-metal affinity chromatography (IMAC). -
エンドトキシン・レベル
< 0.250 Eu/ml -
発現系
Escherichia coli -
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
分子量情報
41.3 kDa -
タグ
His tag N-Terminus
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab93005 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
Mass Spectrometry
Western blot
ELISA
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製品の状態
Liquid -
備考
This product was previously labelled as Annexin A2
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.4
Constituent: 100% PBS
関連情報
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別名
- Annexin A2
- Annexin II
- Annexin II, heavy chain
see all -
機能
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. -
配列類似性
Belongs to the annexin family.
Contains 4 annexin repeats. -
ドメイン
A pair of annexin repeats may form one binding site for calcium and phospholipid. -
翻訳後修飾
Phosphorylation of Tyr-24 enhances heat stress-induced translocation to the cell surface.
ISGylated. -
細胞内局在
Secreted > extracellular space > extracellular matrix > basement membrane. Melanosome. In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism. - Information by UniProt
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プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab93005 は 4 報の論文で使用されています。
- Liu T et al. Cancer-associated fibroblast-specific lncRNA LINC01614 enhances glutamine uptake in lung adenocarcinoma. J Hematol Oncol 15:141 (2022). PubMed: 36209111
- Klabklai P et al. Annexin A2 Improves the Osteogenic Differentiation of Mesenchymal Stem Cells Exposed to High-Glucose Conditions through Lessening the Senescence. Int J Mol Sci 23:N/A (2022). PubMed: 36293376
- Ye Q et al. The important roles and molecular mechanisms of annexin A2 autoantibody in children with nephrotic syndrome. Ann Transl Med 9:1452 (2021). PubMed: 34734004
- Vais H et al. ER-luminal [Ca2+] regulation of InsP3 receptor gating mediated by an ER-luminal peripheral Ca2+-binding protein. Elife 9:N/A (2020). PubMed: 32420875