Recombinant human Angiopoietin 2/ANG2 protein (ab123226)
Key features and details
- Expression system: CHO cells
- Purity: > 95% SDS-PAGE
- Active: Yes
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE, HPLC, Functional Studies
製品の詳細
-
製品名
Recombinant human Angiopoietin 2/ANG2 protein
Angiopoietin 2/ANG2 タンパク質・ペプチド 製品一覧 -
精製度
> 95 % SDS-PAGE.
Purity is greater than 95% by SDS-PAGE gel and HPLC analyses. -
発現系
CHO cells -
アクセッション番号
-
タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
-
生物種
Human -
配列
DAPLEYDDSV QRLQVLENIM ENNTQWLMKL ENYIQDNMKK EMVEIQQNAV QNQTAVMIEI GTNLLNQTAE QTRKLTDVEA QVLNQTTRLE LQLLEHSLST NKLEKQILDQ TSEINKLQDK NSFLEKKVLA MEDKHIIQLQ SIKEEKDQLQ VLVSKQNSII EELEKKIVTA TVNNSVLQKQ QHDLMETVNN LLTMMSTSNS AKDPTVAKEE QISFRDCAEV FKSGHTTNGI YT -
領域
68 to 299 -
タグ
His tag C-Terminus
-
関連製品
-
Related Products
特性
Our Abpromise guarantee covers the use of ab123226 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
アプリケーション
SDS-PAGE
HPLC
Functional Studies
-
製品の状態
Lyophilized -
備考
Determined by its ability to stimulate tubulogenesis in HUVEC cells using a concentration of 0.2µg/ml.This product was previously labelled as Angiopoietin 2
-
Concentration information loading...
前処理および保存
-
保存方法および安定性
Shipped at 4°C. Store at -20°C.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
-
再構成We recommend storing the lyophilised product at -20ºC. If the product has been reconstituted, then we recommend storing with a carrier protein, such as 0.1% BSA in working aliquots at -20ºC to -80ºC for 3 months.
関連情報
-
別名
- AGPT 2
- Agpt2
- ANG 2
see all -
機能
Can induce tyrosine phosphorylation of TIE2. Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. -
配列類似性
Contains 1 fibrinogen C-terminal domain. -
ドメイン
The Fibrinogen C-terminal domain mediates interaction with the TEK/TIE2 receptor. -
細胞内局在
Secreted. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
-
Datasheet download
参考文献 (0)
ab123226 は論文での使用が確認できていません。