Recombinant Human Amino-terminal enhancer of split protein (ab104756)

製品の概要

  • 製品名
    Recombinant Human Amino-terminal enhancer of split protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMMFPQSRHSGSSHLPQQLKFTTSDSCDRIK DEFQLLQAQYHSLKLECDKLASEKSEMQRHYVMYYEMSYGLNIEMHKQAE IVKRLNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELNSIIRQQLQAH QLSQLQALALPLTPLPVGLQPPSLPAVSAGTGLLSLSALGSQAHLSKEDK NGHDGDTHQEDDGEKSD
    • 分子量
      24 kDa including tags
    • 領域
      1 to 197
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab104756 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 95 % SDS-PAGE.
    ab104756 is purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0

関連情報

  • 別名
    • aes
    • Aes 1
    • Aes 2
    • AES_HUMAN
    • Aes1
    • Aes2
    • Amino enhancer of split
    • Amino terminal enhancer of split
    • Amino-terminal enhancer of split
    • Esp 1
    • Esp1
    • Gp130 associated protein GAM
    • Gp130-associated protein GAM
    • GRG
    • GRG 5
    • GRG protein
    • Grg-5
    • GRG5
    • Groucho-related protein 5
    • Protein ESP 1
    • Protein ESP1
    • Protein GRG
    • TLE 5
    • TLE5
    see all
  • 機能
    Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development.
  • 組織特異性
    Found predominantly in muscle, heart and Placenta. In fetal tissues, abundantly expressed in the heart, lung, kidney, brain and liver.
  • 配列類似性
    Belongs to the WD repeat Groucho/TLE family.
  • ドメイン
    Lacks the C-terminal WD repeats.
  • 翻訳後修飾
    Ubiquitinated by XIAP/BIRC4.
  • 細胞内局在
    Nucleus.
  • Information by UniProt

画像

  • 15% SDS-PAGE (3µg).

参考文献

ab104756 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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