製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      PVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQPQPVQPQPHQPMQP QPPVHPMQPLPPQPPLPPMFPMQPLPPMLPDLTLEAWPSTDKTKREEVD
    • 分子量
      37 kDa including tags
    • 領域
      93 to 191

特性

Our Abpromise guarantee covers the use of ab114630 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • AI1E
    • AIH1
    • ALGN
    • Amel
    • Amelogenesis imperfecta 1
    • Amelogenin
    • Amelogenin (amelogenesis imperfecta 1, X linked)
    • Amelogenin (X chromosome)
    • Amelogenin (X chromosome, amelogenesis imperfecta 1)
    • Amelogenin X isoform
    • Amelogenin, X linked
    • AMELX
    • AMELX_HUMAN
    • Amg
    • AMGL
    • AMGX
    • OTTHUMP00000022906
    • OTTHUMP00000022907
    • X isoform
    see all
  • 機能
    Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.
  • 関連疾患
    Defects in AMELX are the cause of amelogenesis imperfecta hypoplastic type 1 (AIH1) [MIM:301200]. AIH1 is a X-linked defect of dental enamel formation. Teeth have only a thin layer of enamel with normal hardness. The thinness of the enamel makes the teeth appear small.
  • 配列類似性
    Belongs to the amelogenin family.
  • 発生段階
    Transiently but abundantly expressed by ameloblasts during tooth development. Amelogenin is the predominant protein in developing dental enamel.
  • 細胞内局在
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt

画像

  • ab114630 analysed by 12.5% SDS-PAGE and stained with Coomassie Blue.

参考文献

ab114630 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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