製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MRTQQKRDTKFREDCPPDREELGRHSWAVLHTLAAYYPDLPTPEQQQDMA QFIHLFSKFYPCEECAEDLRKRLCRNHPDTRTRACFTQWLCHLHNEVNRK LGKPDFDCSKVDERWRDGWKDGSCD
    • 分子量
      40 kDa including tags
    • 領域
      1 to 125

関連製品

特性

Our Abpromise guarantee covers the use of ab114811 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • ALR_HUMAN
    • Augmenter of liver regeneration
    • ERV1
    • ERV1 homolog
    • Erv1 like growth factor
    • FAD-linked sulfhydryl oxidase ALR
    • GFER
    • Growth factor augmenter of liver regeneration
    • Growth factor erv1 like
    • Hepatic regenerative stimulation substance
    • Hepatopoietin
    • Hepatopoietin protein
    • hERV1
    • HPO
    • HPO1
    • HPO2
    • HSS
    see all
  • 機能
    Isoform 1: FAD-dependent sulfhydryl oxidase. Within the mitochondrial intermembrane space, participates in a chain of disulfide exchange reactions with MIA40, that generate disulfide bonds in a number of resident proteins with twin Cx3C and Cx9C motifs.
    Isoform 2: May act as an autocrine hepatotrophic growth factor promoting liver regeneration.
  • 組織特異性
    Ubiquitously expressed. Highest expression in the testis and liver and low expression in the muscle.
  • 関連疾患
    Defects in GFER are a cause of mitochondrial progressive myopathy with congenital cataract hearing loss and developmental delay (MPMCHD) [MIM:613076]; also called combined mitochondrial complex deficiency.
  • 配列類似性
    Contains 1 ERV/ALR sulfhydryl oxidase domain.
  • 細胞内局在
    Mitochondrion intermembrane space and Cytoplasm. Secreted.
  • Information by UniProt

画像

  • 12.5% SDS-PAGE Stained with Coomassie Blue

参考文献

ab114811 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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