Recombinant Human AKR1D1 protein (ab125483)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHH SSGLVPRGSH MDLSAASHRI PLSDGNSIPI IGLGTYSEPK STPKGACATS VKVAIDTGYR HIDGAYIYQN EHEVGEAIRE KIAEGKVRRE DIFYCGKLWA TNHVPEMVRP TLERTLRVLQ LDYVDLYIIE VPMAFKPGDE IYPRDENGKW LYHKSNLCAT WEAMEACKDA GLVKSLGVSN FNRRQLELIL NKPGLKHKPV SNQVECHPYF TQPKLLKFCQ QHDIVITAYS PLGTSRNPIW VNVSSPPLLK DALLNSLGKR YNKTAAQIVL RFNIQRGVVV IPKSFNLERI KENFQIFDFS LTEEEMKDIE ALNKNVRFVE LLMWRDHPEY PFHDEY
    • 分子量
      40 kDa including tags
    • 領域
      1 to 326
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab125483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度
    > 90 % SDS-PAGE.
    ab125483 is purified by proprietary chromatographic techniques.
  • 製品の状態
    Liquid
  • 備考
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C. Store under desiccating conditions.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

関連情報

  • 別名
    • 3-oxo-5-beta-steroid 4-dehydrogenase
    • 3o5bred
    • AK1D1_HUMAN
    • AKR1D1
    • Aldo keto reductase family 1 member D1
    • aldo keto reductase family 1 member D1 (delta 4 3 ketosteroid 5 beta reductase)
    • Aldo-keto reductase family 1 member D1
    • CBAS2
    • Delta(4) 3 ketosteroid 5 beta reductase
    • Delta(4) 3 oxosteroid 5 beta reductase
    • Delta(4)-3-ketosteroid 5-beta-reductase
    • Delta(4)-3-oxosteroid 5-beta-reductase
    • SRD5B1
    • steroid 5 beta reductase
    • steroid 5 beta reductase beta polypeptide 1 (3 oxo 5 beta steroid delta 4 dehydrogenase beta 1)
    see all
  • 機能
    Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as substrates.
  • 組織特異性
    Highly expressed in liver. Expressed in testis and weakly in colon.
  • 関連疾患
    Congenital bile acid synthesis defect 2
  • 配列類似性
    Belongs to the aldo/keto reductase family.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt

参考文献

ab125483 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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