製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MDSKHQCVKL NDGHFMPVLG FGTYAPPEVP RSKALEVTKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSTFH RPELVRPALE NSLKKAQLDY VDLYLIHSPM SLKPGEELSP TDENGKVIFD IVDLCTTWEA MEKCKDAGLA KSIGVSNFNR RQLEMILNKP GLKYKPVCNQ VECHPYFNRS KLLDFCKSKD IVLVAYSALG SQRDKRWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTA EDMKAIDGLD RNLHYFNSDS FASHPNYPYS DEY

特性

Our Abpromise guarantee covers the use of ab87417 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.
    ab87417 is purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • 備考Endotoxin: < 1.0 EU per 1 µg of protein (determined by LAL method).
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, pH 8.0

関連情報

  • 別名
    • 17 beta HSD 5
    • 17 beta hydroxysteroid dehydrogenase type 5
    • 17-beta-HSD 5
    • 17-beta-hydroxysteroid dehydrogenase type 5
    • 2-dihydrobenzene-1
    • 2-diol dehydrogenase
    • 20-alpha-hydroxysteroid dehydrogenase
    • 3 alpha hydroxysteroid dehydrogenase type II
    • 3-alpha-HSD type 2
    • 3-alpha-HSD type II
    • 3-alpha-HSD type II, brain
    • 3-alpha-hydroxysteroid dehydrogenase type 2
    • AK1C3_HUMAN
    • AKR1 C3
    • Akr1c18
    • AKR1C3
    • Aldo keto reductase family 1 member C3
    • Aldo-keto reductase family 1 member C3
    • brain
    • Chlordecone reductase
    • Chlordecone reductase homolog HAKRb
    • DD-3
    • DD3
    • DDH1
    • DDX
    • Dihydrodiol dehydrogenase 3
    • Dihydrodiol dehydrogenase type I
    • Dihydrodiol dehydrogenase X
    • HA1753
    • HAKRB
    • HAKRe
    • hluPGFS
    • HSD17B5
    • Indanol dehydrogenase
    • KIAA0119
    • PGFS
    • Prostaglandin F synthase
    • Testosterone 17-beta-dehydrogenase 5
    • Trans-1
    • Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
    • Type IIb 3 alpha hydroxysteroid dehydrogenase
    see all
  • 機能Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone.
  • 組織特異性Expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. The dominant HSD in prostate and mammary gland. In the prostate, higher levels in epithelial cells than in stromal cells. In the brain, expressed in medulla, spinal cord, frontotemporal lobes, thalamus, subthalamic nuclei and amygdala. Weaker expression in the hippocampus, substantia nigra and caudate.
  • 配列類似性Belongs to the aldo/keto reductase family.
  • 細胞内局在Cytoplasm.
  • Information by UniProt

Recombinant Human AKR1C3 protein 画像

  • 15% SDS-PAGE showing 3µg ab87417 at approximately 39kDa.

Recombinant Human AKR1C3 protein (ab87417) 使用論文

ab87417 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab87417.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"