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Our Abpromise guarantee covers the use of ab90834 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
The exchange of Gln227 to Leu227 (Q/L mutation) in the catalytic site abolishes the intrinsic GTPase activity and increases the GDP-affinity of GSalpha, resulting in a constitutively active G-protein.
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4
This product is an active protein and may elicit a biological response in vivo, handle with caution.
ab90834 has not yet been referenced specifically in any publications.