Recombinant human ADBR2 + Gia3 fusion protein (ab90750)

製品の概要

  • 製品名Recombinant human ADBR2 + Gia3 fusion protein
  • タンパク質長Full length protein
  • 製品の詳細
    Recombinant human ADBR2 + Giα3 fusion protein

法規制情報

製品の詳細

  • 由来Recombinant
  • 由来Baculovirus infected Sf9 cells
  • アミノ酸配列
    • 生物種Human
    • 分子量90 kDa
    • 配列の追加情報Tagged at the N terminus of the ADBR2 with a DDDDK tag. The C terminus of the ADBR2 is linked to the N terminus of the Gi alpha 3 with a His tag.

特性

Our Abpromise guarantee covers the use of ab90750 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性Activity: 7.6 pmol/mg.
  • アプリケーション

    Functional Studies

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • ADRB2
    • ADRB2R
    • ADRBR
    • Adrenergic beta 2 receptor surface
    • B2AR
    • BAR
    • beta 2 adrenoceptor
    • Beta 2 adrenoreceptor
    • BETA2AR
    • Catecholamine receptor
    • G(i) alpha 3
    • Guanine nucleotide binding protein G(k) subunit alpha
    see all
  • 関連性ADBR2 is a member of the G protein-coupled receptor superfamily. It is activated by the catecholamine epinephrine and couples to the G protein Gs to mediate adenylate cyclase activation. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. Gia3 (GNAI3) is the alpha subunit of inhibitory trimeric G protein (Gi), which inhibits adenylate cyclase once its G protein coupled receptors (GPCR) such as a2 adrenergic receptors are activated. GNAI3 can be inactivated by pertussis toxin. Guanine nucleotide binding proteins are involved as modulators or transducers in various transmembrane signaling systems. Gia3 is the stimulatory G protein of receptor-regulated K+ channels.
  • 細胞内局在ADBR2: Cell Membrane

Recombinant human ADBR2 + Gia3 fusion protein (ab90750) 使用論文

ab90750 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"